Shakeib asked on Telegram
can you test Vyper contracts using OpenZeppelin Test Environment?
We assume that Vyper .json artifacts are different from the Solidity generated .json artifacts. If so, contract.fromArtifact is unlikely to work.
The rest of OpenZeppelin Test Environment is not Solidity specific, so it should still be usable, provided you find a way to create a JavaScript contract object from your Vyper generated .json file.