There is an issue open about a possible https://github.com/OpenZeppelin/openzeppelin-contracts/issues/3940
I made some comments there about my findings, did you in OpenZeppelin did any experiment in this topic?
Hey @RenanSouza2, I just took a quick look and left my comments.
We haven't experimented in depth with that since it's for the next 5.0 release we're planning for later this year, but feel free to keep sharing your benchmarks, they definitely help us make a decision 
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